iS Clinical Super Serum Advance +

1 fl oz / Treatments & Serums / Serum

Skip to product information
1 of 1

Expert Advice: This serum promotes even, healthy skin, utilizing Arbutin and Mushroom Extracts to provide safe and effective brightening perfect for hyperpigmentation or melasma.


Earn +1580 Loyalty Points with this order

Free US Shipping for Orders Over $40

Never receive a fake product

iS Clinical Super Serum Advance +

iS Clinical Super Serum Advance +

1 fl oz / Serum / Treatments & Serums

Regular price $158.00
Regular price Sale price $158.00
Sale Sold out
Shipping calculated at checkout.

Product Benefits

  • Diminishes dark spots and scars
  • Brightens and evens skin tone
  • Helps reduce fine lines and wrinkles

Expert Advice: This serum promotes even, healthy skin, utilizing Arbutin and Mushroom Extracts to provide safe and effective brightening perfect for hyperpigmentation or melasma.

View full details

Collapsible content

Product Description

Brighten and protect skin with iS Clinical Super Serum Advance+.

A scientifically advanced, clinically proven formula that combines 15% Vitamin C with peptides, plus powerful botanical antioxidants and safe skin brighteners. Diminish dark spots and scars while reducing the appearance of fine lines and wrinkles.

Key Ingredient: Vitamin C and Hyaluronic acid

How to Use

Apply 3-4 drops to the palm of hand. Using fingertips, dab and smooth evenly over face and neck.


Water/Aqua/Eau, Ascorbic Acid, Hyaluronic Acid, Pentylene Glycol, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Calcium Pantothenate, Zinc Sulfate, Urea, Glucose, Guanidine HCl, Tripeptide-1, Glycerin, Phenoxyethanol, Asiaticoside, Asiatic Acid, Madecassic Acid.

Shipping & Returns

Shipping Policy

Thank you for visiting and shopping at The following includes the terms and conditions that constitute our Shipping Policy.

Domestic Shipping Policy

Shipment processing time

Select products are eligible for same-day shipping, all other orders are processed within 2-3 business days. Orders are not shipped or delivered on weekends or holidays. Orders being shipped to Hawaii and Alaska may take up to 45 to 65 days to be delivered

If we are experiencing a high volume of orders, shipments may be delayed by a few days. Please allow additional days in transit for delivery. If there will be a significant delay in shipment of your order, we will contact you via email or telephone.

Shipping rates & delivery estimates

We value our customers and want to make sure they get the products without a cost (standard shipping.) We will cover your shipping cost.

Order Updates or Cancellations: Orders are processed as soon as we receive it so we can get your order to you as soon as possible. Should you have to update or cancel your order for orders that were placed after 2:00PM EST, please contact us prior to 10AM EST.

Contact Us:

  • Call us at 833-894-SKIN (7546)

  • Send an email with your order number to


You have 30 calendar days to return an item from the date you received it.

To be eligible for a return, your item must be unused and in the same condition that you received it.

Your item must be in the original packaging.

Your item needs to have the receipt or proof of purchase.

Contact Us:

  • Call us at 833-894-SKIN (7546)

  • Send an email with your order number to

Customer Reviews

Based on 46 reviews
Lee L.
Like it so far...

I've only been using this serum for a few weeks, so I'm not quite sure if I'm seeing results yet. It is a very thin consistency (like water) so you have to be careful when putting it on. It does sting a little if I've just done some serious exfoliation or dermaplaning.

Powerful serum

Using it consistently can make a big difference in how your skin looks. Love this product and buy it every time. I noticed the improvement of how my complexion looks, younger and brighter.

Gail Ritter
Great Product!

Love it so far. It definitely has brightened my skin.

Phyllis Michaels
IS Clinical Ptoducts

I have been using their products for years I am turning 70 and everyone thinks I’m in my 50’s.

Tammy S.
Awesome serum!

This serum helps my wrinkles and fine lines. I love that ISClinical products are made with all-natural ingredients, which is very important to me!


Do you have a question, concern, or need help selecting a product? We're here for you!


With all purchases

Earn Rewards

With our loyalty program


Or return within 30 days


For orders over $40